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CS-W001157 4
Total: USD 88.00

Dicyclopropylmethanamine

  • CAS No. 13375-29-6

  • Cat. No. CS-W019419
  • Molecule weight111.19
  • Purity≥97%
  • MDL No.MFCD06804453

*For research and further manufacturing use only, not for direct human use.

Dicyclopropylmethanamine|CS-W019419

Structure of 13375-29-6

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General Information

  • CAS No. 13375-29-6
  • Cat. No. CS-W019419
  • Purity ≥97%
  • MDL No. MFCD06804453
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₃N
  • Molecular Weight 111.19
  • Synonym(s) Dicyclopropane Methylamine
  • SMILES NC(C1CC1)C2CC2

Description

Dicyclopropylmethanamine delivers a sterically hindered, bench-stable amine scaffold ideal for coupling reactions and asymmetric synthesis. This cyclic amine features enhanced nucleophilicity and reduced basicity compared to typical aliphatic amines, enabling selective transformations under mild conditions.

Application

Dicyclopropylmethanamine serves as a versatile chiral auxiliary and amine building block in synthetic organic chemistry. Its rigid bicyclic structure imparts excellent stereocontrol in asymmetric transformations, while the tertiary amine functionality enables efficient protonation and salt formation. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for use in enantioselective synthesis, catalyst design, and the construction of bioactive heterocyclic scaffolds.

Synthesis

  • Route1
    • Dicyclopropylmethanone oxime|CS-0361249
      1453-52-7
    • ~81%
    • In-stock
      Dicyclopropylmethanamine|CS-W019419
      13375-29-6

    References

    • Baruah, Bipul; Dutta, Manu P.; Boruah, Anima; Prajapati, Dipak; Sandhu, Jagir S. Synlett, 1999 , # 4 p. 409 - 410
  • Route2

    References

    • Journal of Medicinal Chemistry, , vol. 39, # 12 p. 2379 - 2391
  • Route3

    References

    • Journal of Organic Chemistry, , vol. 60, # 24 p. 7718 - 7719

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS05,GHS07
Signal Word : Danger
UN#: 2734
Class : 8(3)
Packing Group : Ⅱ
Hazard Statements : H302-H226-H314-H335
Precautionary Statements : P210-P233-P240-P241-P242-P243-P260-P264-P270-P271-P280-P301+P310-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P312-P330-P363-P370+P378-P403+P233-P403+P235-P405-P501

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   1.1337
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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