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Structure of 1359704-84-9
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tert-Butyl 2-oxo-6-azaspiro[3.5]nonane-6-carboxylate is a sterically hindered spirocyclic ketone featuring a nitrogen atom at the bridgehead position. This configuration imparts enhanced stability and facilitates selective functionalization in complex molecular architectures. The tert-butyl ester group enables straightforward deprotection under mild acidic conditions, streamlining access to the corresponding carboxylic acid.
tert-Butyl 2-oxo-6-azaspiro[3.5]nonane-6-carboxylate serves as a versatile spirocyclic building block for medicinal chemistry, enabling access to nitrogen-containing heterocycles via controlled reductive amination and cyclization. The protected ketone and amine functionalities exhibit excellent functional group tolerance, facilitating downstream transformations. Bench-stable and readily purified by chromatography, it supports scalable synthesis of complex scaffolds relevant to drug discovery programs.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: