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Structure of 1363381-18-3
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This spirocyclic scaffold features a protected amine and carboxylic acid moiety, enabling direct incorporation into peptide macrocycle synthesis. The tert-butyl carbamate group provides stability under standard conditions, while the rigid spiro architecture imparts conformational control.
2-[(tert-Butoxy)carbonyl]-2-azaspiro[3.5]nonane-7-carboxylic acid serves as a robust spirocyclic building block for medicinal chemistry, enabling the construction of complex nitrogen-containing heterocycles. Its tert-butyl ester and carboxylic acid functionalities offer orthogonal reactivity, facilitating selective derivatization and incorporation into peptide-like scaffolds. The spirocyclic core provides conformational rigidity and enhanced metabolic stability, making it valuable in lead optimization campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: