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Structure of 1426136-04-0
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5-Amino-2-fluoro-4-methylbenzonitrile features a trifunctional aromatic core enabling direct integration into complex molecular architectures. The electron-donating amino group pairs with the electron-withdrawing nitrile and fluorine substituents, creating a balanced polarity profile ideal for pharmaceutical intermediates. This bench-stable derivative supports efficient coupling reactions under standard conditions.
5-Amino-2-fluoro-4-methylbenzonitrile serves as a versatile building block in medicinal chemistry, enabling the synthesis of fluorinated aromatic scaffolds through standard coupling and functional group interconversions. Its ortho-fluoro and para-amino groups facilitate directed metallation and electrophilic substitution, while the nitrile moiety supports downstream transformations into carboxylic acids, amides, or heterocycles. Bench-stable and compatible with common purification methods, it functions effectively in multi-step synthetic sequences for API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: