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Structure of 1467728-93-3
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Methyl 2-bromo-1-methyl-1H-imidazole-4-carboxylate is a bench-stable, moisture-tolerant heterocyclic building block featuring a brominated imidazole core and ester functionality. This electrophilic scaffold integrates readily into cross-coupling reactions, enabling efficient access to functionalized imidazolyl derivatives for medicinal chemistry and materials science applications.
Methyl 2-bromo-1-methyl-1H-imidazole-4-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling direct functionalization at the C2 position via palladium-catalyzed cross-coupling reactions. The bromo group exhibits high reactivity in Suzuki, Stille, and Negishi transformations, while the methyl imidazole core provides structural rigidity and polarity useful in medicinal chemistry scaffolds. Bench-stable and readily purified by flash chromatography, it functions as a key intermediate in the construction of bioactive imidazoles and pharmaceutical candidates requiring selective substitution patterns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: