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Structure of 1480-66-6
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6-Chloro-2-(trifluoromethyl)pyrimidin-4-amine is a bench-stable heterocyclic building block featuring a chlorine substituent and a trifluoromethyl group at electron-deficient positions. This combination enhances reactivity in cross-coupling processes, enabling efficient incorporation into pharmaceutical scaffolds and agrochemical intermediates under standard conditions.
6-Chloro-2-(trifluoromethyl)pyrimidin-4-amine serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyrimidine-based scaffolds. Its chloro group facilitates nucleophilic substitution reactions with amines and thiols, while the trifluoromethyl moiety enhances metabolic stability and lipophilicity. The amine functionality supports direct coupling or derivatization, offering broad utility in API development. Bench-stable and readily purified, it functions reliably in standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: