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Structure of 151157-44-7
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This cyclobutane carboxylic acid derivative features a 2-bromophenyl group directly attached to the cyclobutane ring, delivering a rigid, electron-deficient aromatic moiety. The carboxylic acid functionality enables direct coupling or derivatization in synthetic workflows. The molecule exhibits enhanced stability and solubility under standard conditions, facilitating use in medicinal chemistry and materials synthesis.
1-(2-Bromophenyl)cyclobutane-1-carboxylic acid serves as a versatile building block for medicinal chemistry and synthetic organic applications. The cyclobutane core provides conformational rigidity, while the ortho-bromophenyl moiety enables palladium-catalyzed cross-coupling reactions. Its carboxylic acid functionality facilitates derivatization via esterification, amide formation, or activation for peptide coupling. The compound exhibits good bench stability and is compatible with standard purification techniques, making it suitable for iterative synthesis and scaffold diversification in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: