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CS-W001157 4
Total: USD 88.00

Tetrakis(dimethylamino)diboron

  • CAS No. 1630-79-1

  • Cat. No. CS-0135678
  • Purity≥95%
  • MDL No.MFCD00048012

*For research and further manufacturing use only, not for direct human use.

Tetrakis(dimethylamino)diboron|CS-0135678

Structure of 1630-79-1

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General Information

  • CAS No. 1630-79-1
  • Cat. No. CS-0135678
  • Purity ≥95%
  • MDL No. MFCD00048012
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₂₄B₂N₄
  • Molecular Weight 197.92
  • Synonym(s) Tetrakis(dimethylamino)diborane
  • SMILES CN(C)B(N(C)C)B(N(C)C)N(C)C

Description

Tetrakis(dimethylamino)diboron delivers a highly reactive, moisture-tolerant diboron source featuring four dimethylamino groups that enhance solubility and stability. This compound enables efficient boron incorporation in cross-coupling reactions, particularly in late-stage functionalization workflows where robustness under standard conditions is essential.

Application

Tetrakis(dimethylamino)diboron serves as a stable, bench-friendly boron source for Suzuki-Miyaura cross-coupling reactions. It enables efficient C–C bond formation with aryl and vinyl halides under mild conditions, offering high functional group tolerance and compatibility with diverse reaction setups. Its crystalline form facilitates handling and purification, making it a practical choice for iterative synthesis in medicinal chemistry and process development workflows.

Synthesis

  • Route1
    • null|null
      6562-41-0
    • ~78%
    • In-stock
      Tetrakis(dimethylamino)diboron|CS-0135678
      1630-79-1

    References

    • Journal of the American Chemical Society, , vol. 82, p. 6242 - 6245 B: B-Verb.4, 9.1, page 268 - 279
  • Route2
    • null|null
      6990-27-8
    • ~80%
    • In-stock
      Tetrakis(dimethylamino)diboron|CS-0135678
      1630-79-1

    References

    • US2974165 , ; C., , p. 17381 DE1138788 , ; C.A., , vol. 58, p. 4597
  • Route3
    • In-stock
      2,2'-Bibenzo[d][1,3,2]dioxaborole|CS-W019123
      13826-27-2
    • null|null
      3585-33-9
    • ~67%
    • In-stock
      Tetrakis(dimethylamino)diboron|CS-0135678
      1630-79-1

    References

    • US6683199 B1, ; Page/Page column 9-10 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H315-H319
Precautionary Statements : P210-P264-P280-P302+P352-P362+P364-P370+P378-P403-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.96
  • LogP   -0.7124
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   5

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