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Structure of 16498-81-0
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2-Methoxynicotinic acid is a bench-stable, moisture-tolerant heterocyclic carboxylic acid featuring a methoxy group at the 2-position of the pyridine ring. This electronic and steric configuration enhances solubility in polar organic solvents and facilitates direct incorporation into pharmaceutical intermediates, coupling reactions, and bioactive molecule scaffolds without requiring protection or derivatization.
2-Methoxynicotinic acid serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted nicotinamide derivatives and heterocyclic scaffolds. Its methoxy group enhances solubility and modulates electronic properties, while the carboxylic acid functionality facilitates direct coupling reactions or derivatization under standard conditions. The compound exhibits good bench stability and is compatible with common functional group transformations, making it a practical choice for synthesizing bioactive molecules and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H319
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Precautionary Statements : P264-P280-P305+P351+P338-P337+P313
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Lot numbers can be found on the outside label of a product: