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Structure of 168644-93-7
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2,4,5-Trifluorobenzylamine features a trifluoromethylated benzyl scaffold with electron-withdrawing fluorine atoms at the 2, 4, and 5 positions. This configuration imparts enhanced metabolic stability and lipophilicity, making it a valuable building block in medicinal chemistry for targeted CNS-penetrant drug candidates.
2,4,5-Trifluorobenzylamine serves as a valuable building block in medicinal chemistry, enabling the synthesis of fluorinated aromatic scaffolds. Its trifluoromethylbenzyl functionality offers enhanced metabolic stability and modulated lipophilicity. The primary amine group facilitates straightforward derivatization via amidation, alkylation, or reductive amination, while the molecule exhibits good bench stability and compatibility with standard purification techniques.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 2735
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: