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Structure of 169280-83-5
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tert-Butyl (5-(hydroxymethyl)pyridin-2-yl)carbamate delivers a pyridine scaffold with a pendant hydroxymethyl group, enabling downstream functionalization through oxidation or coupling reactions. This bench-stable derivative features enhanced solubility and compatibility in aqueous-organic media, simplifying its integration into multi-step synthetic sequences.
tert-Butyl (5-(hydroxymethyl)pyridin-2-yl)carbamate serves as a versatile pyridine-based building block, enabling selective functionalization at the 5-position. The pendant hydroxymethyl group facilitates oxidation to carboxylic acid, reduction to alcohol, or derivatization via Mitsunobu or esterification reactions. The Boc-protected amine offers stability and orthogonality in multi-step syntheses, while the pyridine scaffold provides a reliable platform for medicinal chemistry campaigns targeting kinase inhibitors and other bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: