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Structure of 1780188-78-4
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4-(Difluoromethyl)-3-fluorobenzoic acid features a strategically positioned difluoromethyl group that enhances metabolic stability and lipophilicity, while the ortho-fluoro substituent modulates electronic properties. This combination delivers improved membrane permeability and target engagement potential in bioactive molecule design.
4-(Difluoromethyl)-3-fluorobenzoic acid serves as a versatile building block for fluorinated aromatic systems, enabling the incorporation of both difluoromethyl and trifluoromethyl-like electronic effects. Its stability under standard reaction conditions facilitates direct derivatization into amides, esters, and heterocycles, supporting applications in medicinal chemistry and agrochemical scaffold development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P501
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Lot numbers can be found on the outside label of a product: