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CS-W001157 4
Total: USD 88.00

4-methylamino-2-methanesulfanyl-pyrimidine-5-carboxaldehyde

  • CAS No. 185040-32-8

  • Cat. No. CS-W000299
  • Purity≥97%
  • MDL No.MFCD04115117

*For research and further manufacturing use only, not for direct human use.

4-methylamino-2-methanesulfanyl-pyrimidine-5-carboxaldehyde|CS-W000299

Structure of 185040-32-8

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General Information

  • CAS No. 185040-32-8
  • Cat. No. CS-W000299
  • Purity ≥97%
  • MDL No. MFCD04115117
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉N₃OS
  • Molecular Weight 183.23
  • Synonym(s) 4-METHYLAMINO-2-METHYLSULFANYL-PYRIMIDINE-5-CARBALDEHYDE
  • SMILES CNc1nc(SC)ncc1C=O

Synthesis

  • Route1

    References

    • SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH Patent: WO2004/63195 A1, 2004 ; Location in patent: Page 53-54 ; WO 2004/063195 A1
  • Route2
    • Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate Avanafil  Impurity|CS-0228709
      5909-24-0
    • ~0%
    • In-stock
      ethyl 4-methylamino-2-methyl-thiopyrimidine-5-carboxylate|CS-W000293
      76360-82-2
    • In-stock
      4-methylamino-2-methanesulfanyl-pyrimidine-5-carboxaldehyde|CS-W000299
      185040-32-8

    References

    • Warner-Lambert Company Patent: US5733914 A1, 1998 ;
  • Route3
    • Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate Avanafil  Impurity|CS-0228709
      5909-24-0
    • ~%
    • In-stock
      4-methylamino-2-methanesulfanyl-pyrimidine-5-carboxaldehyde|CS-W000299
      185040-32-8

    References

    • Journal of Medicinal Chemistry, , vol. 41, # 17 p. 3276 - 3292

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   54.88
  • LogP   1.0527
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   3

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