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Structure of 186602-93-7
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This bench-stable arylmethanol features a para-trifluoromethyl group and an ortho-amino functionality, enabling direct incorporation into pharmaceutical scaffolds. The amino group facilitates derivatization, while the trifluoromethyl moiety enhances metabolic stability and lipophilicity in bioactive molecules.
(2-Amino-4-(trifluoromethyl)phenyl)methanol serves as a valuable building block in medicinal chemistry, enabling the synthesis of heterocyclic scaffolds and functionalized arylamines. Its amine and alcohol functionalities offer orthogonal reactivity for derivatization, while the trifluoromethyl group imparts metabolic stability and enhanced lipophilicity. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for use in iterative synthetic sequences and API intermediate development.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H290-H318
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Precautionary Statements : P234-P280-P390-P406
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Lot numbers can be found on the outside label of a product: