2-Methylquinolin-8-amine

Name: 2-Methylquinolin-8-amine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 18978-78-4
Cat. No. CS-W002143
Purity≥98%
MDL No.MFCD00023998

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 18978-78-4

Size

Price

Quantity

* Please select Quantity before adding items.

Description

2-Methylquinolin-8-amine features a sterically accessible quinoline scaffold with a strategically positioned amino group at the 8-position, enabling direct incorporation into transition metal-catalyzed coupling reactions. The methyl substitution enhances electronic modulation and improves solubility in common organic solvents, facilitating use in synthetic workflows requiring stable, bench-ready heterocyclic building blocks.

Application

2-Methylquinolin-8-amine serves as a versatile building block in medicinal chemistry, enabling direct access to quinoline-based scaffolds prevalent in kinase inhibitors and antimalarial agents. Its ortho-amino functionality facilitates electrophilic substitution, metal-catalyzed coupling, and cyclization reactions under standard conditions. The methyl group enhances metabolic stability and modulates electronic properties, while the amine provides a handle for derivatization via acylation, alkylation, or reductive amination. Bench-stable and readily purified by recrystallization, it functions reliably in multi-step synthesis and scale-up workflows.

General Information

CAS No. 18978-78-4
Cat. No. CS-W002143
Purity ≥98%
MDL No. MFCD00023998
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₀N₂
Molecular Weight 158.20
Synonym(s) 8-Aminoquinaldine
SMILES Cc1ccc2c(n1)c(N)ccc2

Computational Chemistry Data

TPSA 38.91
LogP 2.12542
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05,GHS07
Signal Word : Danger	UN#: 1759
Class : 8	Packing Group : Ⅲ
Hazard Statements : H302-H318
Precautionary Statements : P264-P270-P280-P330-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds quinoline compounds

Key Words

2-Methylquinolin-8-amine sigma2-Methylquinolin-8-amine manufacturer2-Methylquinolin-8-amine price2-Methylquinolin-8-amine structure2-Methylquinolin-8-amine SDSbuy 2-Methylquinolin-8-amine2-Methylquinolin-8-amine supplier2-Methylquinolin-8-amine uses2-Methylquinolin-8-amine molecular weightprice of 2-Methylquinolin-8-amine2-Methylquinolin-8-amine chemical name formula of 2-Methylquinolin-8-amine

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Methylquinolin-8-amine

CAS No. 18978-78-4

Recommended Products