(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(oxazol-5-yl)propanoic acid

Name: (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(oxazol-5-yl)propanoic acid
Brand: ChemScene
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CAS No. 1956434-67-5
Cat. No. CS-0128588
Purity≥97%
MDL No.MFCD28134507

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(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(oxazol-5-yl)propanoic acid|CS-0128588

Structure of 1956434-67-5

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Description

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(oxazol-5-yl)propanoic acid features a chiral center flanked by a fluorenylmethoxycarbonyl (Fmoc) protecting group and a sterically constrained oxazol-5-yl side chain. This combination enables efficient incorporation into peptide synthesis workflows, offering enhanced solubility and stability under standard coupling conditions.

Application

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(oxazol-5-yl)propanoic acid serves as a valuable chiral building block in peptide synthesis, enabling efficient incorporation of oxazol-5-yl functionality at the C-terminal position. The Fmoc group provides excellent stability and ease of removal under mild basic conditions, while the oxazol-5-yl side chain offers a robust heterocyclic moiety with proven utility in medicinal chemistry scaffolds. Its compatibility with standard coupling protocols and straightforward purification make it well-suited for both academic and industrial peptide workflows.

General Information

CAS No. 1956434-67-5
Cat. No. CS-0128588
Purity ≥97%
MDL No. MFCD28134507
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₁H₁₈N₂O₅
Molecular Weight 378.38
Synonym(s) (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(1,3-oxazol-5-yl)propanoic acid
SMILES O=C(OCC1C2=CC=CC=C2C3=C1C=CC=C3)N[C@@H](CC4=CN=CO4)C(O)=O

Computational Chemistry Data

TPSA 101.66
LogP 3.209
H_Acceptors 5
H_Donors 2
Rotatable_Bonds 6

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Oxazole compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Alanine and derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

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(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(oxazol-5-yl)propanoic acid

CAS No. 1956434-67-5

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