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Structure of 240401-28-9
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tert-Butyl 2-hydroxy-7-azaspiro[3.5]nonane-7-carboxylate is a sterically shielded spirocyclic scaffold featuring a labile hydroxyl group and a protected carboxylic acid. This configuration enables direct functionalization at the nitrogen center while maintaining stability under standard bench conditions. The tert-butyl ester facilitates convenient deprotection in late-stage synthesis, streamlining access to biologically relevant azaspiroalkane architectures.
tert-Butyl 2-hydroxy-7-azaspiro[3.5]nonane-7-carboxylate serves as a versatile spirocyclic scaffold for medicinal chemistry, enabling the construction of complex nitrogen-containing heterocycles. The pendant hydroxyl group offers direct handle for derivatization, while the tert-butyl ester provides stability and convenient deprotection under mild acidic conditions. Its rigid, three-dimensional architecture enhances ligand-receptor binding selectivity and metabolic stability in bioactive molecule design.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: