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Structure of 20615-18-3
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4,4-Dimethylcyclohexanamine features a sterically hindered amine group within a stable cyclohexane core, enhancing its resistance to over-alkylation. This bench-stable, moisture-tolerant amine integrates readily into synthetic routes requiring a bulky, electron-rich nitrogen donor.
4,4-Dimethylcyclohexanamine serves as a versatile chiral building block in medicinal chemistry, offering enhanced lipophilicity and metabolic stability compared to unsubstituted cyclohexylamines. Its tertiary amine functionality facilitates salt formation and enables efficient derivatization via alkylation or acylation. The gem-dimethyl substitution provides steric shielding and improved bench stability, making it well-suited for use in API synthesis and catalyst development.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 2735
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: