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Structure of 21035-59-6
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N-Methyl-1-(pyridin-2-yl)methanamine features a pyridine ring directly attached to a methylene bridge, bearing a methylated amine group. This configuration imparts enhanced lipophilicity and improved metabolic stability compared to its unsubstituted analog. The compound serves as a key building block in the synthesis of bioactive heterocycles and ligands for transition metal catalysis.
N-Methyl-1-(pyridin-2-yl)methanamine serves as a versatile building block in medicinal chemistry, enabling the construction of pyridine-containing scaffolds via standard coupling and functionalization reactions. Its amine functionality exhibits favorable reactivity in amidation, alkylation, and electrophilic substitution processes, while the pyridine ring provides orthogonal handling for further derivatization. The compound demonstrates bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 2735
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H227-H314-H302
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Precautionary Statements : P210-P260-P264-P270-P280-P301+P310-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P363-P370+P378-P403+P235-P405-P501
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Lot numbers can be found on the outside label of a product: