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Structure of 211308-81-5
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5-Chloro-3-iodo-2-pyridinamine features a strategically positioned chloro and iodo substituent on the pyridine ring, enabling selective cross-coupling reactions. The amine group provides a handle for further functionalization, while the electron-deficient heterocycle enhances reactivity in palladium-catalyzed transformations. This bench-stable intermediate supports efficient access to complex nitrogen-containing architectures in medicinal chemistry and materials synthesis.
5-Chloro-3-iodo-2-pyridinamine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The chloro group facilitates electrophilic substitution or nucleophilic displacement, while the iodo moiety supports efficient Suzuki, Stille, or Negishi coupling under standard conditions. Its bench-stable nature and compatibility with diverse functional groups make it ideal for constructing complex heterocyclic scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: