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CS-W001157 4
Total: USD 88.00

tert-Butyl 3-(hydroxymethyl)benzylcarbamate

  • CAS No. 226070-69-5

  • Cat. No. CS-0041674
  • Purity≥97%
  • MDL No.MFCD06411554
  • HazMat Fee +

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    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 3-(hydroxymethyl)benzylcarbamate|CS-0041674

Structure of 226070-69-5

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Description

tert-Butyl 3-(hydroxymethyl)benzylcarbamate features a benzylcarbamate scaffold with a pendant hydroxymethyl group, enabling direct functionalization or derivatization. The tert-butyl carbamate moiety provides stable protection under standard conditions, while the benzylic alcohol offers a handle for oxidation or coupling reactions. This compound serves as a key intermediate in medicinal chemistry and peptide synthesis.

Application

tert-Butyl 3-(hydroxymethyl)benzylcarbamate serves as a versatile benzylamine-based building block for medicinal chemistry and process synthesis. The pendant hydroxymethyl group enables direct oxidation to aldehyde or carboxylic acid, while the tert-butyl carbamate (Boc) moiety provides stable protection of the amine under acidic conditions. This combination facilitates sequential functionalization and orthogonal deprotection workflows in complex molecule assembly.

General Information

  • CAS No. 226070-69-5
  • Cat. No. CS-0041674
  • Purity ≥97%
  • MDL No. MFCD06411554
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₉NO₃
  • Molecular Weight 237.29
  • Synonym(s) tert-butyl [3-(hydroxymethyl)benzyl]carbamate
  • SMILES CC(C)(C)OC(=O)NCC1=CC=CC(CO)=C1

Computational Chemistry Data

  • TPSA   58.56
  • LogP   2.2036
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H332-H335
Precautionary Statements : P260-P261-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P304+P341-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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