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Structure of 2362-12-1
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4-Bromo-2-methylphenol features a bromine atom at the para position relative to a hydroxyl group and a methyl substituent ortho to the hydroxyl, creating a sterically hindered, electron-deficient aromatic system. This combination enhances its utility in palladium-catalyzed coupling reactions and as a building block for bioactive heterocycles.
4-Bromo-2-methylphenol serves as a valuable building block in medicinal chemistry and agrochemical synthesis, enabling direct functionalization at the phenolic oxygen and ortho-position to the methyl group. Its bromine atom facilitates palladium-catalyzed cross-coupling reactions, while the methyl group provides a site for oxidation or further substitution. The compound exhibits good bench stability and is compatible with standard purification methods, making it a practical choice for iterative synthetic sequences in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: