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Structure of 25513-92-2
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Ethyl 3-methylpyrazine-2-carboxylate features a pyrazine core bearing methyl and ethoxycarbonyl substituents at the 3- and 2-positions, respectively. This electron-deficient heterocycle integrates readily into synthetic routes targeting bioactive alkaloids and pharmaceutical intermediates. The ester functionality enables further derivatization under standard conditions, while the sterically hindered methyl group enhances metabolic stability in complex molecular architectures.
Ethyl 3-methylpyrazine-2-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to pyrazine-based scaffolds relevant to agrochemicals and pharmaceuticals. Its dual functionality—ester and electron-deficient pyrazine ring—facilitates nucleophilic substitution, metal-catalyzed coupling, and reductive transformations under standard conditions. The compound exhibits good bench stability, ease of purification, and compatibility with diverse functional groups, making it well-suited for iterative synthetic strategies in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: