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Structure of 257937-08-9
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tert-Butyl (3-bromopyridin-4-yl)carbamate features a brominated pyridine core with a stable tert-butyl carbamate protecting group, enabling selective functionalization in late-stage diversification. This bench-stable reagent integrates readily into cross-coupling and cyclization workflows, offering controlled access to nitrogen-containing heterocycles under standard conditions.
tert-Butyl (3-bromopyridin-4-yl)carbamate serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the pyridine C3 position via palladium-catalyzed cross-coupling. The carbamate group provides excellent bench stability and facilitates purification, while the bromide enables reliable Suzuki, Stille, and Negishi transformations. Its compatibility with diverse reaction conditions makes it a practical scaffold for constructing biologically active heterocycles and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: