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Structure of 26740-71-6
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4,5-Dichloro-2-methylpyrimidine serves as a versatile heterocyclic scaffold in medicinal chemistry, featuring two chlorine substituents at the 4 and 5 positions and a methyl group at C2. This configuration imparts enhanced reactivity for nucleophilic substitution, enabling efficient coupling with amines and thiols under mild conditions. The molecule exhibits bench-stable handling characteristics and compatibility with diverse reaction media, facilitating its use in building complex pharmacophores.
4,5-Dichloro-2-methylpyrimidine serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient construction of heterocyclic scaffolds via nucleophilic substitution. Its dichloro substituents provide orthogonal reactivity for sequential functionalization, while the methyl group enhances metabolic stability and modulates electronic properties. The compound exhibits excellent bench stability, facilitates straightforward purification, and functions reliably in standard coupling protocols across diverse reaction conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: