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CS-W001157 4
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5-Amino-1-(tert-butyl)-1H-pyrrole-3-carbonitrile

  • CAS No. 269726-49-0

  • Cat. No. CS-M0874
  • Purity≥98%
  • MDL No.MFCD11846194
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Amino-1-(tert-butyl)-1H-pyrrole-3-carbonitrile|CS-M0874

Structure of 269726-49-0

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Description

5-Amino-1-(tert-butyl)-1H-pyrrole-3-carbonitrile features a sterically shielded tert-butyl group that enhances stability and solubility in organic media. The electron-rich pyrrole core, combined with complementary amino and nitrile functionalities, enables direct incorporation into complex heterocycles and facilitates downstream functionalization under mild conditions.

Application

5-Amino-1-(tert-butyl)-1H-pyrrole-3-carbonitrile serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. The tert-butyl group provides steric protection and enhanced bench stability, while the amino and nitrile functionalities enable diverse downstream transformations—such as amidation, cyclization, and metal-catalyzed coupling—facilitating rapid access to functionalized pyrrole scaffolds with high regiocontrol.

General Information

  • CAS No. 269726-49-0
  • Cat. No. CS-M0874
  • Purity ≥98%
  • MDL No. MFCD11846194
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₃N₃
  • Molecular Weight 163.22
  • Synonym(s) 5-amino-1-tert-butylpyrrole-3-carbonitrile
  • SMILES N#CC1=CN(C(C)(C)C)C(N)=C1

Computational Chemistry Data

  • TPSA   54.74
  • LogP   1.69698
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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