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Structure of 29289-13-2
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2-Iodo-4-methylaniline features a para-methyl group and an iodo substituent on the aromatic ring, delivering enhanced reactivity in cross-coupling processes. This bench-stable derivative enables efficient access to functionalized anilines under standard conditions.
2-Iodo-4-methylaniline serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling palladium-catalyzed cross-coupling reactions due to its reactive iodide functionality. The ortho-iodo group facilitates efficient C–C and C–heteroatom bond formation under standard conditions, while the para-methyl aniline moiety provides electronic modulation and enhanced stability. Its bench-stable crystalline form simplifies handling and purification, making it well-suited for iterative synthetic sequences and scale-up applications.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P302+P352-P304+P340
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Lot numbers can be found on the outside label of a product: