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Structure of 307951-53-7
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4-Chloro-2-methyl-1H-pyrrolo[2,3-b]pyridine features a fused bicyclic core with a chlorine substituent at the 4-position and a methyl group at the 2-position, conferring enhanced electron deficiency and improved metabolic stability. This scaffold serves as a key building block in medicinal chemistry for kinase inhibitors and targeted therapeutics.
4-Chloro-2-methyl-1H-pyrrolo[2,3-b]pyridine serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C4 position via palladium-catalyzed cross-coupling reactions. Its methyl group enhances solubility and stability, while the chloro substituent provides high reactivity in Suzuki-Miyaura and Buchwald-Hartwig couplings. The fused heterocyclic core offers structural rigidity and favorable electronic properties for target-directed synthesis.
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: