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Structure of 33016-47-6
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1-Trityl-1H-imidazole-4-carbaldehyde features a trityl-protected imidazole scaffold with a reactive aldehyde group at the C4 position. This derivative enables selective functionalization in synthetic workflows, particularly in nucleoside and oligonucleotide chemistry, where the trityl moiety provides steric shielding and facilitates purification. The aldehyde group serves as a handle for conjugation or further derivatization under mild conditions.
1-Trityl-1H-imidazole-4-carbaldehyde serves as a robust, bench-stable building block for the synthesis of imidazole-based heterocycles and bioactive scaffolds. Its trityl group provides excellent protection for the imidazole nitrogen, enabling selective functionalization at C4. The aldehyde functionality facilitates nucleophilic additions, reductive aminations, and coupling reactions with broad functional group tolerance, making it ideal for iterative synthesis in medicinal chemistry and combinatorial library development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: