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CS-W001157 4
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2-Oxa-7-azaspiro[4.5]decane hydrochloride

  • CAS No. 374795-37-6

  • Cat. No. CS-B0201
  • Molecule weight177.67
  • Purity≥97%
  • MDL No.MFCD13185095

*For research and further manufacturing use only, not for direct human use.

2-Oxa-7-azaspiro[4.5]decane hydrochloride|CS-B0201

Structure of 374795-37-6

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General Information

  • CAS No. 374795-37-6
  • Cat. No. CS-B0201
  • Purity ≥97%
  • MDL No. MFCD13185095
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₆ClNO
  • Molecular Weight 177.67
  • Synonym(s) None
  • SMILES C12(COCC2)CNCCC1.Cl

Description

This spirocyclic heterocycle features a rigid, three-dimensional scaffold that enhances metabolic stability and modulates pharmacokinetic properties. The hydrochloride salt improves solubility and handling, enabling efficient integration into medicinal chemistry campaigns targeting CNS disorders and kinase inhibition pathways.

Application

2-Oxa-7-azaspiro[4.5]decane hydrochloride serves as a versatile spirocyclic scaffold in medicinal chemistry, enabling efficient access to constrained heterocyclic architectures. The molecule exhibits robust bench stability and facilitates functional group tolerance in standard coupling and derivatization reactions. Its rigid, three-dimensional structure enhances target selectivity in biological screening, while the hydrochloride salt improves solubility and handling for synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   1.1983
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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