Bis-propargyl-PEG1

Name: Bis-propargyl-PEG1
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 40842-04-4
Cat. No. CS-0114310
Purity≥98%
MDL No.MFCD03640302

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 40842-04-4

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Description

Bis-propargyl-PEG1 delivers a highly reactive, linear spacer with two terminal alkyne groups, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation and polymer synthesis. The short PEG chain ensures minimal steric hindrance while maintaining solubility in aqueous and organic media. This bifunctional linker streamlines the construction of complex architectures in materials science and chemical biology applications.

Application

Bis-propargyl-PEG1 serves as a versatile, linear spacer for click chemistry applications, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) to construct triazole-linked architectures. Its terminal propargyl groups exhibit high reactivity and stability under standard synthetic conditions, facilitating modular assembly of bioconjugates, polymer linkages, and functionalized scaffolds. The short PEG unit provides solubility and reduced aggregation in aqueous environments, enhancing utility in biological and materials science workflows.

General Information

CAS No. 40842-04-4
Cat. No. CS-0114310
Purity ≥98%
MDL No. MFCD03640302
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₀O₂
Molecular Weight 138.16
Synonym(s) None
SMILES C#CCOCCOCC#C

Computational Chemistry Data

TPSA 18.46
LogP 0.286
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 5

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS02
Signal Word : Danger	UN#: 3271
Class : 3	Packing Group : Ⅲ
Hazard Statements : H226
Precautionary Statements : P210-P233-P240-P241-P243-P280-P370+P378-P501

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Other Classifications

Building Blocks Functional Group PEG

Building Blocks Skeleton Fatty chain compounds

Life Science Linker Alkyne PEG

Life Science Linker Propargyl PEG

Life Science Click Chemistry Reagents

Life Science Crosslinking Agent

Chemical Biology Pharmaceutical Development and Drug Discovery Research Conjugation Chemistry/Click Chemistry Crosslinker Azides/Alkynes

Chemical Biology Pharmaceutical Development and Drug Discovery Research Conjugation Chemistry/Click Chemistry Terminal Alkynes

Chemical Biology Pharmaceutical Development and Drug Discovery Research Bioconjugation PEGylation Reagents and PEG Spacers

Chemical Biology Pharmaceutical Development and Drug Discovery Research Bioconjugation Homobifunctional Cross-Linkers

Chemical Biology Pharmaceutical Development and Drug Discovery Research Linkers and Crosslinkers Homobifunctional Cross-Linkers

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Linkers and Crosslinkers Homobifunctional Cross-Linkers

Chemical Biology Conjugation Chemistry/Click Chemistry Crosslinker Azides/Alkynes

Chemical Biology Conjugation Chemistry/Click Chemistry PEG Azides/Alkynes

Chemical Biology PEGylation Monofunctional PEG and Oligoethylene Glycols

Chemical Biology PEGylation Heterobifunctional PEG and Oligoethylene Glycols

Chemical Biology Linkers and Crosslinkers Homobifunctional Cross-Linkers

Biochemistry Biochemicals and Reagents Bioconjugation PEGylation Reagents and PEG Spacers

Biochemistry Biochemicals and Reagents Bioconjugation Homobifunctional Cross-Linkers

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Bis-propargyl-PEG1

CAS No. 40842-04-4

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