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Structure of 41288-91-9
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6-Chloro-N,N-dimethylpyridin-3-amine features a chlorinated pyridine core with a dimethylamino group at the 3-position, delivering enhanced nucleophilicity and stability under standard conditions. This electron-rich heterocycle integrates efficiently into transition metal-catalyzed coupling reactions, serving as a robust scaffold for synthesizing functionalized pharmaceutical intermediates and advanced materials.
6-Chloro-N,N-dimethylpyridin-3-amine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its reactive chloropyridine moiety. The dimethylamino group enhances electron density at the pyridine ring, facilitating nucleophilic substitution and promoting reactivity in Suzuki-Miyaura and Buchwald-Hartwig couplings. Its bench-stable nature and compatibility with diverse functional groups make it ideal for constructing complex heterocyclic scaffolds in API development.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: