2-Amino-3-nitropyridine

Name: 2-Amino-3-nitropyridine
Brand: ChemScene
Availability: InStock
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CAS No. 4214-75-9
Cat. No. CS-D1021
Purity≥98%
MDL No.MFCD00006314

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 4214-75-9

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Description

2-Amino-3-nitropyridine features a pyridine core bearing amino and nitro groups in close proximity, enabling unique electronic interactions. This configuration supports direct functionalization in cross-coupling and cyclization reactions. The compound exhibits enhanced solubility in polar solvents and stability under standard bench conditions, facilitating its use in synthetic intermediates for pharmaceuticals and agrochemicals.

Application

2-Amino-3-nitropyridine serves as a versatile building block in heterocyclic synthesis, enabling direct functionalization at the 2-amino and 3-nitro positions. Its complementary reactivity facilitates selective reduction, coupling, and cyclization protocols essential for constructing nitrogen-rich scaffolds. The molecule exhibits good bench stability and is readily purified by recrystallization, making it suitable for iterative synthesis workflows in medicinal chemistry and materials science applications.

General Information

CAS No. 4214-75-9
Cat. No. CS-D1021
Purity ≥98%
MDL No. MFCD00006314
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₅N₃O₂
Molecular Weight 139.11
Synonym(s) 3-Nitropyridin-2-ylamine
SMILES NC1=NC=CC=C1[N+]([O-])=O

Computational Chemistry Data

TPSA 82.05
LogP 0.572
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Other Classifications

Bioactive Molecules Dye and Bio-assay Reagents

Building Blocks Functional Group Amine

Building Blocks Functional Group Nitro compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Material Science Photonics/Optical Materials NLO

Material Science Photonic Materials, Optical Materials Organic Non-Linear Optical (NLO) Materials

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2-Amino-3-nitropyridine

CAS No. 4214-75-9

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