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Structure of 429683-46-5
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4-Bromo-2-fluoro-6-methylaniline is a fluorinated aryl amine featuring orthogonal halogen and methyl directing groups, enabling selective functionalization in cross-coupling and electrophilic substitution. This bench-stable derivative integrates readily into complex heterocyclic scaffolds under mild conditions.
4-Bromo-2-fluoro-6-methylaniline serves as a valuable building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-substituted arylamine framework enables efficient coupling reactions, including Suzuki-Miyaura and Buchwald-Hartwig protocols, while the bromo and fluoro groups provide orthogonal reactivity for sequential functionalization. The methyl group enhances metabolic stability and modulates electronic properties, making this compound well-suited for medicinal chemistry campaigns requiring precise substitution patterns and robust bench stability.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: