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Structure of 433926-48-8
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3-Chloro-5-(trifluoromethoxy)benzaldehyde features a trifluoromethoxy group that enhances electron-withdrawing character and metabolic stability, while the chloro substituent introduces steric and electronic modulation. This combination enables efficient incorporation into pharmaceutical intermediates and functional materials. The aldehyde functionality offers direct reactivity for nucleophilic addition and condensation reactions under standard conditions.
3-Chloro-5-(trifluoromethoxy)benzaldehyde serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to functionalized heterocycles and biaryl scaffolds. Its electron-withdrawing trifluoromethoxy group enhances electrophilicity at the aldehyde center, facilitating nucleophilic addition and coupling reactions. The molecule exhibits excellent bench stability and compatibility with standard reaction conditions, allowing straightforward purification and integration into multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: