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Structure of 445303-96-8
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3-(Difluoromethyl)-4-fluoroaniline features a strategically positioned difluoromethyl group that enhances metabolic stability and modulates electronic properties. This electron-deficient arylamine integrates readily into pharmaceutical scaffolds, offering improved bioavailability and resistance to oxidative degradation under standard bench conditions.
3-(Difluoromethyl)-4-fluoroaniline serves as a valuable building block in medicinal chemistry, enabling the introduction of a difluoromethyl group adjacent to a fluorinated aromatic ring. Its stability under standard reaction conditions and compatibility with diverse coupling processes facilitate efficient synthesis of bioactive molecules. The molecule functions effectively in Suzuki-Miyaura and Buchwald-Hartwig couplings, offering a practical route to fluorinated heterocycles and pharmaceutical scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: