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Structure of 450412-22-3
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1-Bromo-2-iodo-3-methoxybenzene features a trifunctional aromatic scaffold with complementary halogen handles for cross-coupling reactions. The methoxy group enhances solubility and directs regioselective transformations, while the bromo and iodo substituents enable sequential functionalization under palladium catalysis. This compound serves as a key intermediate in the synthesis of complex pharmaceuticals and functional materials.
1-Bromo-2-iodo-3-methoxybenzene serves as a versatile dihalogenated aromatic building block for palladium-catalyzed cross-coupling reactions. The orthogonal reactivity of bromo and iodo groups enables sequential functionalization, while the methoxy substituent provides moderate electron donation and enhances solubility. Bench-stable and readily purified by column chromatography, it facilitates efficient access to complex substituted arenes and heterocyclic scaffolds in medicinal chemistry and materials synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: