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Structure of 488713-31-1
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5-Amino-3-chloropicolinonitrile features a trifunctional pyridine core bearing amino, chloro, and nitrile groups in a regioselective arrangement. This electron-deficient heterocycle integrates readily into cross-coupling reactions and serves as a key scaffold for pharmaceutical intermediates, offering enhanced reactivity under standard conditions.
5-Amino-3-chloropicolinonitrile serves as a versatile building block in synthetic organic chemistry, enabling the construction of substituted pyridine scaffolds through standard coupling and cyclization reactions. Its amino and nitrile groups provide orthogonal reactivity for sequential functionalization, while the chlorine substituent facilitates palladium-catalyzed cross-coupling transformations. The compound exhibits good bench stability and is amenable to purification by recrystallization, making it well-suited for use in medicinal chemistry campaigns and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: