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CS-W001157 4
Total: USD 88.00

NSC 127234

  • CAS No. 5509-65-9

  • Cat. No. CS-W020001
  • Purity≥98%
  • MDL No.MFCD00007655
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

NSC 127234|CS-W020001

Structure of 5509-65-9

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Description

2,6-Difluoroaniline was used in the synthesis of:N-2,6-difluorophenyl-5-methoxy-1,2,4-triazolo[1,5-a]pyrimidine-2-sulfonamide, herbicidal compoundseries of 2,6,9-trisubstituted purine inhibitors of p38 kinasesubstituted phenylthiomorpholine dioxide, an active pharmaceutical intermediate

Application

2,6-Difluoroaniline serves as a valuable building block in medicinal chemistry and agrochemical synthesis, offering enhanced metabolic stability and improved solubility compared to unsubstituted anilines. Its ortho-fluoro substituents enable selective electrophilic substitution and facilitate coupling reactions via Pd-catalyzed cross-coupling protocols. The molecule exhibits good bench stability and is compatible with common protecting group strategies, enabling efficient access to complex heterocyclic scaffolds and functionalized aromatic systems in multi-step syntheses.

General Information

  • CAS No. 5509-65-9
  • Cat. No. CS-W020001
  • Purity ≥98%
  • MDL No. MFCD00007655
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅F₂N
  • Molecular Weight 129.11
  • Synonym(s) 7-fluoro-1-benzothiophene-2-carboxylic acid
  • SMILES NC1=C(F)C=CC=C1F

Computational Chemistry Data

  • TPSA   26.02
  • LogP   1.547
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Warning
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P370+P378-P501

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