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Structure of 57443-18-2
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Benzyl 2-(dimethoxyphosphoryl)acetate features a dimethoxyphosphoryl group that enables direct incorporation into phosphonate-containing architectures. This stable, bench-ready reagent facilitates efficient P–C bond formation in synthetic sequences. The benzyl ester moiety offers straightforward deprotection under standard conditions, enabling rapid access to functionalized intermediates.
Benzyl 2-(dimethoxyphosphoryl)acetate serves as a versatile synthon in carbonyl-alkylation and phosphonate-mediated C–C bond formation. Its stabilized α-phosphono ester structure enables reliable Michael additions, Mannich reactions, and Horner–Wadsworth–Emmons olefination with high functional group tolerance. The benzyl ester facilitates straightforward deprotection under mild hydrogenolysis conditions, offering efficient access to key intermediates for heterocyclic synthesis and pharmaceutical building blocks.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362+P364
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Lot numbers can be found on the outside label of a product: