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Structure of 578027-35-7
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(R)-1-[4-(Trifluoromethyl)phenyl]ethylamine is a chiral amine featuring a trifluoromethyl group at the para position of a phenyl ring. This configuration imparts enhanced metabolic stability and lipophilicity, making it a valuable building block in asymmetric synthesis. The molecule integrates readily into pharmaceutical intermediates and functionalized ligands.
(R)-1-[4-(Trifluoromethyl)phenyl]ethylamine serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of asymmetric pharmaceutical intermediates. Its benzylic amine functionality exhibits good bench stability and compatibility with standard functional group manipulations. The trifluoromethyl group imparts enhanced metabolic stability and lipophilicity, making this scaffold particularly useful in drug discovery campaigns targeting CNS and oncology therapeutics.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H319
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Precautionary Statements : P264-P270-P280-P330-P405-P501
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Lot numbers can be found on the outside label of a product: