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CS-W001157 4
Total: USD 88.00

2-Amino-5-methylbenzonitrile

  • CAS No. 5925-93-9

  • Cat. No. CS-W011090
  • Purity≥98%
  • MDL No.MFCD00267506
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Amino-5-methylbenzonitrile|CS-W011090

Structure of 5925-93-9

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Description

2-Amino-5-methylbenzonitrile features a strategically positioned nitrile group flanked by an amino moiety and a methyl substituent, enabling its use in constructing electron-rich heterocycles. This ortho-substituted aromatic scaffold offers enhanced solubility and stability under standard bench conditions, facilitating efficient coupling reactions in synthetic workflows.

Application

2-Amino-5-methylbenzonitrile serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to substituted benzimidazoles, quinoline derivatives, and other heterocyclic scaffolds. Its amino and nitrile groups exhibit complementary reactivity, allowing for sequential functionalization under mild conditions. The compound demonstrates excellent bench stability and is readily purified by recrystallization or column chromatography, facilitating integration into multi-step synthetic sequences.

General Information

  • CAS No. 5925-93-9
  • Cat. No. CS-W011090
  • Purity ≥98%
  • MDL No. MFCD00267506
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈N₂
  • Molecular Weight 132.17
  • Synonym(s) 6-Amino-m-tolunitrile
  • SMILES N#CC1=CC(C)=CC=C1N

Computational Chemistry Data

  • TPSA   49.81
  • LogP   1.4489
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 3439
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301+H311+H331-H315-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P361+P364-P362+P364-P403+P233-P405-P501

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