4-Amino-3-methylbenzonitrile

Name: 4-Amino-3-methylbenzonitrile
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 78881-21-7
Cat. No. CS-W011091
Purity≥95%
MDL No.MFCD02093969

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 78881-21-7

Size

Price

Quantity

* Please select Quantity before adding items.

Description

4-Amino-3-methylbenzonitrile features a strategically positioned amino group adjacent to a nitrile, enabling direct functionalization in pharmaceutical intermediates. The methyl substituent enhances electron density at the aromatic ring, improving reactivity in coupling processes. This bench-stable, moisture-tolerant compound integrates seamlessly into multi-step syntheses requiring controlled polarity and regioselective transformations.

Application

4-Amino-3-methylbenzonitrile serves as a versatile building block for pharmaceutical and agrochemical synthesis, enabling efficient access to substituted benzimidazoles, quinolines, and other heterocyclic scaffolds. Its ortho-directed reactivity facilitates regioselective functionalization, while the amino and nitrile groups offer complementary handles for derivatization. The compound exhibits good bench stability and is amenable to standard purification techniques, supporting its use in multi-step synthetic sequences.

General Information

CAS No. 78881-21-7
Cat. No. CS-W011091
Purity ≥95%
MDL No. MFCD02093969
Storage RT, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₈N₂
Molecular Weight None
Synonym(s) 4-Cyano-o-toluidine
SMILES NC1=C(C=C(C#N)C=C1)C

Computational Chemistry Data

TPSA 49.81
LogP 1.4489
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Cyanide/Nitrile

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

4-Amino-3-methylbenzonitrile sigma4-Amino-3-methylbenzonitrile manufacturer4-Amino-3-methylbenzonitrile price4-Amino-3-methylbenzonitrile structure4-Amino-3-methylbenzonitrile SDSbuy 4-Amino-3-methylbenzonitrile4-Amino-3-methylbenzonitrile supplier4-Amino-3-methylbenzonitrile uses4-Amino-3-methylbenzonitrile molecular weightprice of 4-Amino-3-methylbenzonitrile4-Amino-3-methylbenzonitrile chemical name formula of 4-Amino-3-methylbenzonitrile

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

4-Amino-3-methylbenzonitrile

CAS No. 78881-21-7

Recommended Products