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Thieno[2,3-b]pyridine-2-carboxylic acid

  • CAS No. 59944-76-2

  • Cat. No. CS-0043678
  • Purity≥97%
  • MDL No.MFCD07371381
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Thieno[2,3-b]pyridine-2-carboxylic acid|CS-0043678

Structure of 59944-76-2

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Description

Thieno[2,3-b]pyridine-2-carboxylic acid features a fused heterocyclic core combining thiophene and pyridine units, delivering enhanced electron-withdrawing character and planarity. This structural rigidity supports applications in organic semiconductors and pharmaceutical intermediates, where stable conjugation and defined polarity are critical. The carboxylic acid group enables direct functionalization or salt formation for improved solubility and reactivity under standard conditions.

Application

Thieno[2,3-b]pyridine-2-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science. Its fused thiophene-pyridine core provides enhanced planarity and electron-deficient character, enabling efficient coupling reactions and facilitating incorporation into bioactive scaffolds. The carboxylic acid group offers direct handle for amide formation, esterification, or metal coordination, supporting downstream derivatization. Bench-stable and readily purified by recrystallization, it functions reliably in standard synthetic workflows.

General Information

  • CAS No. 59944-76-2
  • Cat. No. CS-0043678
  • Purity ≥97%
  • MDL No. MFCD07371381
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅NO₂S
  • Molecular Weight 179.20
  • Synonym(s) 2-Carboxythieno[2,3-b]pyridine
  • SMILES O=C(C1=CC2=CC=CN=C2S1)O

Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.9945
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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