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Structure of 60388-38-7
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5-(Trifluoromethyl)benzo[d]thiazol-2-amine features a trifluoromethyl group that enhances electron deficiency and metabolic stability, while the thiazole scaffold provides a rigid, planar architecture ideal for π-stacking interactions. This compound serves as a key building block in bioactive heterocycle synthesis and functional materials development.
5-(Trifluoromethyl)benzo[d]thiazol-2-amine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to bioactive scaffolds through standard coupling reactions. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the amine functionality facilitates derivatization via amidation, alkylation, or cross-coupling. The compound exhibits good bench stability and is compatible with common reaction conditions, making it valuable for lead optimization and API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: