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Structure of 656-65-5
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3-Fluoro-4-bromoaniline is a fluorinated aryl amine featuring complementary halogen handles for cross-coupling. The para-bromo and meta-fluoro substituents enable selective functionalization in Pd-catalyzed reactions. This electron-deficient aniline serves as a key intermediate in synthesizing bioactive heterocycles and pharmaceutical scaffolds under standard conditions.
3-Fluoro-4-bromoaniline serves as a versatile building block for pharmaceutical and agrochemical synthesis, enabling palladium-catalyzed cross-coupling reactions due to its complementary halogen reactivity. The ortho-fluoro and bromo substituents provide orthogonal functionalization potential, facilitating sequential derivatization. Its bench-stable crystalline form simplifies handling and purification, while the electron-withdrawing fluorine enhances regioselectivity in electrophilic substitutions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: