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CS-W001157 4
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6-Chloro-2,3-dihydro-1H-inden-1-amine

  • CAS No. 67120-38-1

  • Cat. No. CS-0101141
  • Molecule weight167.64
  • Purity≥97%
  • MDL No.MFCD07373938

*For research and further manufacturing use only, not for direct human use.

6-Chloro-2,3-dihydro-1H-inden-1-amine|CS-0101141

Structure of 67120-38-1

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General Information

  • CAS No. 67120-38-1
  • Cat. No. CS-0101141
  • Purity ≥97%
  • MDL No. MFCD07373938
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀ClN
  • Molecular Weight 167.64
  • Synonym(s) 1H-INDEN-1-AMINE,6-CHLORO-2,3-DIHYDRO
  • SMILES NC1CCC2=C1C=C(C=C2)Cl

Description

6-Chloro-2,3-dihydro-1H-inden-1-amine features a chlorine-substituted indene core with a primary amine at the 1-position, offering a rigid, electron-deficient scaffold. This structure enables direct incorporation into pharmaceutical intermediates and functional materials, particularly where steric control and moderate lipophilicity are required.

Application

6-Chloro-2,3-dihydro-1H-inden-1-amine serves as a versatile scaffold for medicinal chemistry and catalytic synthesis, offering a rigid, electron-deficient indane core with a primary amine handle. The molecule exhibits excellent bench stability, facilitates straightforward functionalization at the amine site, and enables efficient coupling reactions in standard protocols. Its structure supports incorporation into diverse heterocyclic systems and bioactive molecules, making it a practical building block for API development and process-scale applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.286
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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