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Tetrahydro-2H-pyran-3-amine hydrochloride

  • CAS No. 675112-58-0

  • Cat. No. CS-0069616
  • Purity≥97%
  • MDL No.MFCD08059238

*For research and further manufacturing use only, not for direct human use.

Tetrahydro-2H-pyran-3-amine hydrochloride|CS-0069616

Structure of 675112-58-0

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General Information

  • CAS No. 675112-58-0
  • Cat. No. CS-0069616
  • Purity ≥97%
  • MDL No. MFCD08059238
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₂ClNO
  • Molecular Weight 137.61
  • Synonym(s) TETRAHYDRO-PYRAN-3-YLAMINE HYDROCHLORIDE
  • SMILES NC1COCCC1.[H]Cl

Description

Tetrahydro-2H-pyran-3-amine hydrochloride features a pyranyl nitrogen atom that delivers enhanced solubility and reactivity in synthetic transformations. This bench-stable, moisture-tolerant amine serves as a versatile scaffold for building complex heterocycles and functionalized intermediates in medicinal chemistry and materials science applications.

Application

Tetrahydro-2H-pyran-3-amine hydrochloride serves as a versatile heterocyclic building block for medicinal chemistry and catalytic synthesis. Its primary amine functionality enables straightforward derivatization via alkylation, acylation, or reductive amination, while the tetrahydropyran ring provides metabolic stability and favorable pharmacokinetic properties. The hydrochloride salt ensures excellent solubility and bench stability, facilitating handling and purification in standard laboratory workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   35.25
  • LogP   0.5459
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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