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CS-W001157 4
Total: USD 88.00

4-(morpholinomethyl)-3-(trifluoromethyl)aniline

  • CAS No. 694499-30-4

  • Cat. No. CS-W000764
  • Purity≥97%
  • MDL No.None
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-(morpholinomethyl)-3-(trifluoromethyl)aniline|CS-W000764

Structure of 694499-30-4

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Description

4-(morpholinomethyl)-3-(trifluoromethyl)aniline features a trifluoromethyl group at the meta position and a morpholinomethyl substituent at the para position relative to the amine, creating a uniquely electron-deficient aromatic core with enhanced solubility and metabolic stability. This combination enables direct incorporation into bioactive scaffolds for kinase inhibitor development and pharmaceutical lead optimization.

Application

4-(Morpholinomethyl)-3-(trifluoromethyl)aniline serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through standard coupling and cyclization protocols. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the morpholinomethyl moiety provides a handle for further functionalization. The compound exhibits good bench stability and compatibility with common reaction conditions, facilitating efficient purification and integration into complex molecular architectures.

General Information

  • CAS No. 694499-30-4
  • Cat. No. CS-W000764
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₅F₃N₂O
  • Molecular Weight 260.26
  • Synonym(s) 4-(morpholin-4-ylmethyl)-3-(trifluoromethyl)aniline
  • SMILES FC(F)(F)C1=C(CN2CCOCC2)C=CC(N)=C1

Computational Chemistry Data

  • TPSA   38.49
  • LogP   2.1198
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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