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Structure of 69816-38-2
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2-Amino-5-(trifluoromethyl)pyrazine is a bench-stable, electron-deficient heterocycle featuring a strategically positioned amino group and a strongly polar trifluoromethyl substituent. This combination enables direct incorporation into bioactive molecule scaffolds, particularly in medicinal chemistry applications where enhanced metabolic stability and membrane permeability are required.
2-Amino-5-(trifluoromethyl)pyrazine serves as a versatile heterocyclic building block in medicinal chemistry, enabling the synthesis of bioactive molecules through standard coupling reactions. Its amino and trifluoromethyl groups offer orthogonal reactivity, facilitating functionalization while maintaining stability under common reaction conditions. The molecule exhibits favorable solubility and bench stability, making it well-suited for multi-step synthetic sequences and API development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: